Search results for "Oxygen pressure"

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Tumour oxygenation during fractionated radiotherapy--comparison with size-matched controls.

1999

The effect of fractionated irradiation on the oxygenation status of experimental tumours was investigated using polarographic assessment of the pO2 distribution. Since an improvement in tumour oxygenation could simply be the result of tumour shrinkage, a comparison of pO2 readings of untreated size-matched control tumours was performed. Irradiation was carried out using 6 fractions of 6 Gy applied within 11 days. A comparison of polarographic pO2 data with size-matched untreated tumours revealed a significant improvement in oxygenation after the irradiation. The median pO2 was 0.9+/-0.1 mm Hg for unirradiated tumours at a volume of 180 mm3, while the corresponding data for irradiated tumour…

inorganic chemicalsFractionated radiotherapymedicine.medical_treatmentTransplantation HeterologousMice NudeMiceOxygen ConsumptionMedicineAnimalsHumansRadiology Nuclear Medicine and imagingddc:610Oxygen pressurebusiness.industryDose-Response Relationship RadiationHematologyGeneral MedicineOxygenationrespiratory systemTumour oxygenationSpecific Pathogen-Free OrganismsRadiation therapyOncologyEstablished cell lineFractionated irradiationNeurofibrosarcomacardiovascular systemDose Fractionation RadiationbusinessNuclear medicineNeoplasm Transplantationcirculatory and respiratory physiologyActa oncologica (Stockholm, Sweden)
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Lung Injury Is a Predictor of Cerebral Hypoxia and Mortality in Traumatic Brain Injury

2020

Background: A major contributor to unfavorable outcome after traumatic brain injury (TBI) is secondary brain injury. Low brain tissue oxygen tension (PbtO2) has shown to be an independent predictor of unfavorable outcome. Although PbtO2 provides clinicians with an understanding of the ischemic and non-ischemic derangements of brain physiology, its value does not take into consideration systemic oxygenation that can influence patients' outcomes. This study analyses brain and systemic oxygenation and a number of related indices in TBI patients: PbtO2, partial arterial oxygenation pressure (PaO2), PbtO2/PaO2, ratio of PbtO2 to fraction of inspired oxygen (FiO2), and PaO2/FiO2. The primary aim …

medicine.medical_specialtyTraumatic brain injuryLung injurylcsh:RC346-42903 medical and health sciences0302 clinical medicineInternal medicineFraction of inspired oxygenmedicinecerebral oxygenationCerebral perfusion pressurelung injurylcsh:Neurology. Diseases of the nervous systemIntracranial pressureOriginal Researchpartial arterial oxygen pressurebusiness.industrycerebral oxygenation; hypoxia threshold; lung injury; mortality outcome; partial arterial oxygen pressure; traumatic brain injurymortality outcometraumatic brain injuryCerebral hypoxiaNeurointensive care030208 emergency & critical care medicinehypoxia thresholdrespiratory systemmedicine.diseaseOxygen tensionrespiratory tract diseasesNeurologyCardiologyNeurology (clinical)business030217 neurology & neurosurgerycirculatory and respiratory physiologyFrontiers in Neurology
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